The basis of ED herbal therapies is that they are anti-inflammatory, antioxidant and immunomodulatory, and can stimulate testosterone production. On the other hand, the synthetic drugs act via NO. The principal mediator of the relaxation of corporal smooth muscle of the penis has been shown to be NO, which is released mainly from parasympathetic nerves and endothelium [13]. NO is believed to relax the corporal smooth muscle by activating soluble guanylate cyclase to increase cGMP content [14,15]. Penile rigidity depends on maximizing inflow of blood while minimizing outflow [6]. The increased blood flow in the cavernous sinuses puts pressure on the walls of the surrounding veins, causing the lumen of the veins narrow, temporarily interfering with the flow of blood but causing tumescence. Normally, the parasympathetic nerve produces Ach. Ach acts on muscarinic receptors and nicotinic cholinergic receptors. When the parasympathetic nerve is stimulated, preganglionic neurons release Ach at the ganglion, which acts on nicotinic receptors on postganglionic receptors. Postganglionic neurons then release Ach to stimulate muscarinic receptors of the target organs. The muscarinic receptor M3, present in the endothelial cells and smooth muscle, is activated, and the M2 receptor in the heart may also be activated. This may result in the production of Ach, which can cause endothelial cells to produce NO. Ach released from postganglionic parasympathetic nerves acting through G-protein-mediated muscarinic receptors and nicotinic cholinergic receptors helps to release NO. Normally, M1, M2 and M3 receptors are found in secretory glands, heart, smooth muscle and endothelial cells, respectively. M1, M2 and M3 receptors cause activation of phospholipase C and generate inositol trisphosphate and diacylglycerol, which increase calcium. Activation of M4 may inhibit adenylate cyclase, decreasing the messenger cyclic AMP. This mechanism may be involved in the relaxation and contraction of cavernosal smooth muscle cells.
By doing Kegels, it’s actually possible to tone up the bulbocavernosus muscle. This muscle is extremely important for men. Thus, it lets the penis to fill with blood in order an erection could occur. The muscle also pumps during the process of ejaculation. In addition, it allows emptying the urethra after you urinate. The study has indicated that it’s necessary to perform Kegel exercises 2 times per day for at least 3 months to achieve considerable results.

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'After my divorce, I began dating again and met a few lovely women. But -can you believe it - every time I 'got lucky', the whole thing fell flat and I just couldn't perform! Exercise helped a bit, but I just wasn't the man I used to be. Things were going from bad to worse and I even stopped dating because I was so anxious! Eventually a friend told me about Ikawe and I thought 'What have I got to lose?' Six weeks later, I just can't get enough and nor can my new girlfriend! What a difference!' - Stewart, U.K.
ED can also occur as a side effect of some medications, for example some high blood pressure medications such as certain diuretics and beta blockers. If you think that a medication you are taking has a negative effect on your sex life, you should discuss this with your prescribing doctor. Your doctor may be able to recommend an alternative treatment.
In addition, when research has shown a nutrient such as zinc or niacin to improve sexual function, it's usually in people who are deficient in it. So, before you stock up on over-the-counter nutritional supplements for ED, speak with your doctor. He can test you for deficiencies and steer you toward the most effective and safest way to treat your erectile dysfunction. 
Yohimbe (Pausinystalia yohimbe): again an Asian favorite which originates from an evergreen tree native to the West African Countries of Congo, Cameroon and Gabon, it is the only herb listed in the Physician’s Index Reference as supporting sexual function. Its Latin name is Pausinystalia yohimbe. The USA FDA approved yohimbe as the first plant derived drug for treating impotency long ago and was dubbed the herbal viagra II in the February 1999 edition of Environmental Nutrition. Alkaloid in yohimbe i.e., Iso Yohimbine, allo-yohimbine, yohimbinine, yohimbane, yohimbenine and corynantheine blocks alpha-2 adrenergic activity allowing vasodilation. It also acts as a monoamine oxidase inhibitor increasing serotonin in the brain. Yohimbine has a dual aphrodisiac function: it improves sexual function (10) by displacing epinephrine from alpha-2 adrenergic receptors in the pelvic area and it increases proneness to arousal thru supplying the epinephrine from the alpha-2 receptors to the central nervous system (brain) where it is active as a neurotransmitter. Side effects include nervousness, anxiety, insomnia, and possibly mild hypertension (5).

Males suffer with ED due to hormonal imbalance. Tufan capsules are the best ED pills as these can resolve the problem occurring due to hormonal fluctuations as well. These herbal ED pills provide natural treatment by suppressing hormonal fluctuations induced by insomnia, stress, medicines, health conditions, age and bad habits. When males have hormonal secretion in right quantity and proper balance they are able to maintain optimum functions of reproductive system and keep at bay problems like ED. Males leading stressful life, unable to exercise, inactive during the day and taking medicines or in habit of alcohol, smoking etc., easily exhaust their reproductive system, Tufan are reckoned as the best ED pills as these capsules alleviate the problem by handling all these causes effectively.
From the researchers' point of view, the usage of herbal remedies in managing male sexual disorders is useful because of long cultural history of utilisation and the current renewed interest in natural products to sustain health globally. As a way recognising the values and roles of traditional medical knowledge in health care provision, further research into the efficacy and safety of herbal remedies in male sexual disorders is precious in Uganda and beyond. More so, the establishment of rapport between relevant government department in Ministry of Health, modern health workers through collaborative and networking ventures with traditional healers under close supervision and monitoring of herbal treatments is noble.
Erectile dysfunction is a common problem in men of all ages than publicly perceived. Since, I started the research in reproductive health care; the commonest question asked by men is related with medicinal plants that empower male sexuality. So far, several males have been consulting on the treatment of ED using herbal remedies, either by themselves or through friends12.
Epimedium extract (Horny Goat Weed) (11), (Figure 9): the Chinese refer to this herb as ‘yin yang huo’, which has been loosely translated as ‘licentious goat plant’; hence, its common name is well known as ‘horny goat weed’ by many Western cultures. Scientifically, studies have shown that Epimedium may restore low levels of both testosterone and thyroid hormone, bringing low levels back to their normal levels (5), which may account for some of its benefits in improving sexual libido. Other benefits to Epimedium involve increased muscle mass. Used for fatigue and aging, And vasodilatation effect; thus, most frequently used in treatment of sexual dysfunction in Traditional Chinese Medicine (12). The active substance from horny goat weed was reported by Xin Zhong Cheng at Beijing Medical University as Icarin—acts by increasing sexual activities and ICP levels in castrated rats after long term oral administration. It has no effects on serum testosterone level in castrated rats after long term oral administration. Instead Icariin increases nNOS and iNOS mRNA and protein expression in the corpus cavernosum after long term oral administration and hence may have long term efficacy on erectile dysfunction after oral administration.
Erectile Dysfunction (ED) is a common problem in men. In fact, half of all men have erectile dysfunction at some level. That is the condition that a man cannot achieve or maintain an erection. It can result in guilt and depression. There are various reasons for erectile dysfunction. However, they are classified into two categories – physical and psychological. Researchers have shown that about 70 percent of cases of this condition come from physical causes and the rest comes from psychological causes.

Physical and emotional stress — whether over-exercising, under-sleeping or just dealing with everyday stressors like work and a busy schedule — causes an increase in “stress hormones,” including cortisol and adrenaline. Stress can lower desire for sex. This is because stress can contribute to fatigue or preoccupation with other tasks. It can also significantly affect blood flow by increasing inflammation.
Generally speaking, the juice and other extracts from this are always in high demand for treating ED. This extract is increasing in popularity because it is very rich in vital nutrients. Better still; some researchers also admit that it facilitates the expansion of arteries and sustain supply. For its holistic health advantages, it is recommended for you and other victims of ED.
There’s one more thing to remember: A visit to a physician can be helpful even if a man doesn’t want to go near Viagra or try one of the alternatives. In some cases, a treatable medical condition such as low testosterone or depression could explain a case of ED. “Sexual health should not be viewed as a luxury, but rather as an essential component to wellness,” said urologist Ryan P. Terlecki, MD, of Wake Forest Baptist Health in North Carolina.
Ashwagandha’s reputation as a sexual enhancement herb is supported by research. One animal study showed that extracts of ashwagandha increased production of sex hormones and sperm, presumably by exerting a testosterone-like effect. In another clinical trial, the herb (taken at a dose of 3 gm per day for 1 year) was given to healthy male adults 50–59 years of age. Among benefits noted: serum cholesterol levels decreased, gray hair was reduced, and a vast majority (over 70%) reported improvement in sexual performance.
Men can judge themselves pretty harshly when it comes to their performance in between the sheets. The unsettling fear of not being able to rise to the occasion becomes a reccurring nightmare for men that is often equated with failure, loss of dignity, and masculinity. If you suffer from erectile dysfunction (ED), don’t be so hard on yourself, since impotence can almost always be improved with treatment, without having to rely on Viagra or other medications. Whether you suffer from ED, or hope to prevent the condition, here are six tips to overcome impotence without the side effects of the little blue pill.

Erectile dysfunction (ED) is defined as the “inability to reach and maintain erection during the intercourse” (1) leading to the victim’s experience of inadequate libido, inefficient orgasm and retarded or premature ejaculation. In Recent times, ED has been labeled as the most common sexual problem among pleasure-seeking males and a complaint of all men irrespective of their age, race and culture but age is the most important risk factor for ED (2). It is reported that nearly 100 million people around the world are living with erectile dysfunction. Yet, only 10% of these 100 million, i.e., 10 million are opting for treatment, despite enormous advancements and treatment facilities in all parts of the world (2). To cite a few countries, in China and Korea only 9% and 30% males voluntarily admit to having ED (2) and in most of the other countries in Asia, it is still considered very sensitive with considerable social stigma and secretly will resort to herbal remedies and tonics before seeking conventional medical help.


These three versatile herbs, used for centuries in Chinese and Ayurvedic medicine, have a variety of health benefits for both men and women. However, they work in several ways to address health issues of top concern to men, such as erectile dysfunction (ED) and high blood pressure, and I believe they should be a part of every man’s long-term plan for overall health.
When you are stressed, your body has to overwork to fight off the stress. Hence you will lose much energy to deal with this condition. Besides, trying to have sex makes the body have to face new stress. This results in the lack of erections. So, if you want to prevent erectile dysfunction, stress is the thing you need to eliminate immediately. Dr. Julian Nesbitt said: “Stress releases cortisol which can negative physical effects as well as emotional psychological effects which you being stressed you may be less likely to maintain an erection. Try to take time for your self and try breathing/ relaxation exercises.” 
And just because you’re using a “natural” herb doesn’t mean you won’t feel any side effects. Ginseng can cause hypoglycemia or bleeding in some people, and at high doses puncturevine can damage the kidneys. Plus, the FDA has found that a lot of supplement companies make sure their erection-enhancing products actually produce erections by tossing in some Viagra off-label. If you really need it, it’s probably better–and safer–to go see your doctor for a prescription.
Masturbating and watching porn cause negative impacts on both physical and mental health. These activities make too much sexual stimulation. Hence the brain will get overloaded. However, giving them up is not easy and you need time to make things normal again. Dr. Julian Nesbitt said: “Watching porn has a negative psychological effect as can make your expectation of sex unrealistic and therefore you are no longer aroused by your regular partner. Make sure your open with your partner about what turns you on to have a better overall sexual experience.”

Feeling fatigued, very stressed, depressed or dealing with another mood-related issue that can lower libido. Sources of stress and diminished quality of life — such as “deteriorating economic position,” unhappiness with one’s job or other aspects that lower emotional health — are believed to be major causes for sexual dysfunction in both men and women
In one study, men with a Vitamin D deficiency were nearly 33% more likely to have ED. But you don’t need that much sun exposure to get a healthy amount of Vitamin D. As little as 15–20 minutes a day is enough. Taking Vitamin D is a good idea, especially if you are over 65. Vitamin D can also help if you’re obese or dark-skinned (dark skin limits the amount of Vitamin D you naturally, produce)
In diabetes, vasoconstrictors and vasoactive factors are increased in addition to structural changes and attenuation of relaxation responses in the corpus cavernosum. A shifting of the balance of vasoactive factors occurs such that relaxation factors (eg, nitric oxide [NO]) are inhibited and contractile factors are induced in microvascular disease. With epidemiological predictions suggesting that the incidence of diabetes mellitus will increase to 300 million by 2025, management of diabetes-induced ED is increasingly important.
ED can be caused by a handful of things, but one thing’s for sure: You need a healthy supply of the neurotransmitter nitric oxide (NO) to get and maintain an erection. NO is produced in nerve tissue and helps jolt your Johnson by relaxing the smooth muscle so blood can fill the penis. After the initial release of NO, your body releases a cascade of chemicals—including more of the neurotransmitter—to help keep you hard and happy, according to a study in the Proceedings of the National Academy of Sciences.
This is the vegetable root from Peru that meets the entire health benefits. If you can add this to your diet, you will surely see the difference. Maca is highly rich in iodine, amino acids, iron and magnesium. There are three types of Maca; black, red and yellow. The black one appears to get rid of stress as you boost your memory. Stress could cause ED.
Pay attention to your vascular health. High blood pressure, high blood sugar, high cholesterol, and high triglycerides can all damage arteries in the heart (causing heart attack), in the brain (causing stroke), and leading to the penis (causing ED). An expanding waistline also contributes. Check with your doctor to find out whether your vascular system — and thus your heart, brain, and penis — is in good shape or needs a tune-up through lifestyle changes and, if necessary, medications.

Saw palmetto. Saw palmetto comes from the fruit of a small palm tree. It has been used to treat symptoms in men with an enlarged prostate gland, such as difficulty urinating, and it has been recommended to treat ED caused by an enlarged prostate. However, several recent clinical trials did not show that saw palmetto works any better on an enlarged prostate than a placebo does. "There is no evidence that saw palmetto should be used to treat erectile dysfunction," says Dr. Gilbert. Like ginkgo biloba, saw palmetto can interact with some prescription medications.
Eleutherococcus senticosis (Siberian Ginseng) is an overall system toner and improves performance and stamina. In the 1950's it was used extensively by Soviet athletes to enhance athletic performance. It can combat stress and is a tonic stimulant for the adrenal hormones. One of the most important active ingredients in Siberian or Oriental Ginseng is the ginsenosides, which greatly promote blood flow to the brain and peripherals, including the penis. In oriental medicine, Ginseng is highly respected and prized as a herb which promotes male or 'yang' energy, improving circulation, boosting vitality and acting as an overall systemic invigorator.
There is growing evidence that acupuncture which is an ancient treatment method is helpful for rebuilding the men’s sex life. This treatment option implies the insertion of needles into the special points on skin in order to reduce pain, as well as to overcome stress and depression. There are points responsible for the men’s sexual health. According to different researches, acupuncture can be successfully used as an ED cure. For example, the study conducted in 1999 has indicated that the application of this treatment technique helped revive erectile function and increased the frequency of sexual activity in 39% of men. Acupuncture cures mild to moderate ED caused by psychological factors.
There is a wide range of methods including different medications for healing sexual disabilities in men. But nowadays more and more men are refusing from the use of outdated erectile dysfunction treatment techniques and synthetic medications. That’s why men replace them with the latest natural remedies able to gently cure the impairment of erectile function without the interference with bodily functions. Male Extra and VigRX belong to such remedies. These supplements offer the most innovative solution for the elimination of erectile dysfunction symptoms without any harm to the men’s health. These products are highly effective because they contain only the natural, fully safe active substances.
In addition, when research has shown a nutrient such as zinc or niacin to improve sexual function, it's usually in people who are deficient in it. So, before you stock up on over-the-counter nutritional supplements for ED, speak with your doctor. He can test you for deficiencies and steer you toward the most effective and safest way to treat your erectile dysfunction. 
I found the process of ordering the medication very easy and the communication from your company was excellent. I also thank you most sincerely in respect the processing of my order, the delivery. and excellent manner in which my medication was packaged and sent to me. In addition my goods arrived in good condition and on the date as stated. All round an excellent service from Dr. ED for which I am very grateful and which I strongly recommend to everyone.
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