Your doctor may also choose to lower your dose of certain medications. Or your provider may switch the type of drug you’re taking if it’s interfering with your sex life. Some medicines used for managing blood pressure, insomnia, anxiety, depression, seizures and prostate problems increase the risk for erectile dysfunction. Beta-blockers (for high blood pressure), SSRIs (often used to treat depression) and the class of drugs called benzodiazepines (like Ativan, Xanax, Librium and Valium) are commonly tied to ED. You may want to speak to your doctor about this.

Erectile dysfunction can occur as a side effect of medication taken for another health condition. Common culprits are high blood pressure meds, antidepressants, some diuretics, beta-blockers, heart medication, cholesterol meds, antipsychotic drugs, hormone drugs, corticosteroids, chemotherapy, and medication for male pattern baldness, among others.
“Obecalp” is “placebo” spelled backwards. It might help – treatment with inactive placebos (inert substances used in evaluation of new drug treatments) works about one-third of the time in scientific studies when patients don’t know they’re getting a fake drug. Placebos are generally safe since they contain no known active agent. (However, I personally never give patients inactive placebos, and many physicians regard them as unethical.)
'After my divorce, I began dating again and met a few lovely women. But -can you believe it - every time I 'got lucky', the whole thing fell flat and I just couldn't perform! Exercise helped a bit, but I just wasn't the man I used to be. Things were going from bad to worse and I even stopped dating because I was so anxious! Eventually a friend told me about Ikawe and I thought 'What have I got to lose?' Six weeks later, I just can't get enough and nor can my new girlfriend! What a difference!' - Stewart, U.K.
A study published in May 2014 in The Journal of Sexual Medicine found that some men can reverse erectile dysfunction with healthy lifestyle changes, such as exercise, weight loss, a varied diet, and good sleep. The Australian researchers also showed that even if erectile dysfunction medication is required, it's likely to be more effective if you implement these healthy lifestyle changes.

The treatment effect of both these treatments were tested by making the participants of the study fill up the International Index of Erectile Function (IIEF) and Satisfaction Profile (SAT-P) questionnaires before and after the treatment (i.e. maca extract supplementation or placebo). Higher score in these questionnaires mean better erectile function.
No matter what erectile dysfunction treatment or treatments (whether herbal remedies or not) a man ultimately decides upon, experts say it's important to eat healthily and to avoid smoking and heavy drinking. Moreover, adequate exercise, stress reduction, and sleep can improve erectile dysfunction in many. In addition, says Lamm, "A loving, receptive, and responsive partner is a home run. After all, this is still a couple's issue."
Half of the men in the study (50%) were able to complete sexual intercourse in more than 75% of attempts. A comparison of all the above mentioned parameters (NPT, hormone profile and the Florida Sexual Health Questionnaire) before and after yohimbine supplementation clearly showed that men who had milder erectile dysfunction showed improvement while those with severe erectile dysfunction failed to show much improvement.
In addition, this amino acid increases sperm volume and makes sperm quality better. Moreover, L-Arginine is most effective for men with initially low NO levels. Thus, this amino acid normalizes endothelial nitric oxide synthesis. That contributes to the vascular function restoration, including penile vascular function. The amino acid prevents aging changes in the blood vessels and dramatically reduces the harmful effects of nicotine on arteries with capillaries.

For a male, sexual performance carries an identity and the sense of self-esteem in his society. Thus, Sexual performance in the male has an unprecedented importance depending on the erectile function of the male sex organ. In daily life, it is very easy for men to admit having a sore throat or hemorrhoids. However, admitting to having erectile dysfunction is contrary to the male ego and especially so if the dysfunction occurs when he is at mid-life and is getting older and there any suspicion of him entering the phase of male menopause.
Yohimbine is the principal alkaloid of the bark of the West African evergreen P johimbe (formerly known as C johimbe), family Rubiaceae. The main active chemical present in P johimbe bark is yohimbine hydrochloride (an indole alkaloid), which has stimulant and aphrodisiac effects. However, the levels of yohimbine that are present in P johimbe bark extract are variable and often very low. Therefore, although P johimbe bark has traditionally been used to treat ED [38], there is insufficient scientific evidence to form a definitive conclusion in this area. It is an antagonist of α2-receptors and has no direct relation to erection. It acts as a sex motivation stimulant. Yohimbine has been used as both an over-the-counter dietary supplement in the form of an herbal extract, and as a prescription medicine in purified form for the treatment of sexual dysfunction. Yohimbine 20 mg or adjusted dose has been found to be effective in the treatment of orgasmic dysfunction. Yohimbine was recently associated as a treatment for type 2 diabetes mellitus in animal and human models carrying polymorphisms of the alpha-2A adrenergic receptor gene [39]. The National Institutes of Health states that yohimbine hydrochloride is the standardized form of yohimbine that is available as a prescription medicine in the United States, and has been shown in human studies to be effective in the treatment of male impotence. Yohimbine hydrochloride USP has been used to treat ED. Controlled studies suggest that it is not always an effective treatment for impotence, and evidence of increased sex drive (libido) is anecdotal only. It cannot be excluded that orally administered yohimbine can have a beneficial effect in some patients with ED. The conflicting results available may be attributed to differences in drug design, patient selection and definition of positive response. Yohimbine has been shown to be effective in the reversal of sexual satiety and exhaustion in male rats, and has also been shown to increase the volume of ejaculated semen in dogs, with the effect lasting at least 5 h after administration. Yohimbine has also been shown to be effective in the treatment of orgasmic dysfunction in men, and has also been used for the treatment of sexual side effects caused by some antidepressants, and female hyposexual disorder. Yohimbine has significant side effects, such as anxiety reactions. Higher doses of oral yohimbine may create numerous side effects, such as rapid heart rate, high blood pressure, overstimulation, insomnia and/or sleeplessness. More serious adverse effects may include seizures and renal failure. Yohimbine should not be consumed by individuals with liver, kidney or heart disease, or psychological disorders. The therapeutic index of yohimbine is low; the range between an effective dose and a dangerous dose is very narrow. Side effects include gastrointestinal upset, increased blood pressure, headache, agitation, rash, tachycardia and frequent urination [40].
From the bark of an evergreen tree in West Africa, Yohimbine has been used as a treatment for erectile dysfunction for the last 70 years. Like many over-the-counter and prescription erectile dysfunction medications, Yohimbine helps to increase the potentially stalled blood flow in the penis, increases overall sexual desire, and helps boost adrenaline. Yohimbine has also been known to help men gain, prolong, and maintain erections.
Phytolacca dodecandra leaves and roots are pounded and smeared on ripe banana and then the ripe banana roasted before being eaten for treating erectile dysfunction. However, care has to be taken Phytolacca dodecandra is poisonous. Cola acuminata fruits are mixed with other plants in Benin to treat primary and secondary sterility24. Cola acuminata is also said to be diuretic and laxative when administered orally24. Some Acacia species are regarded as aphrodisiacs in Niger2. Cassia species have high repute as drugs and poisons. For instance, Cassia sieberiana is used urinary problems, impotence and kidney diseases in Mali24. In Burkina Faso, Cassia occidentalis is used as a stimulant24. Flueggea virosa is famous medicine in African cultures. Flueggea virosa used in sterility, aphrodisiacs, stimulant, rheumatism, arthritis, spermatorrhoea, kidney and liver problems among many other diseases treated17,24.
Tufan capsules are reckoned as the best ED pills as these possess only natural herbs as ingredients. Using Tufan herbal ED pills is safe as the herbs present in these pills are highly effective and completely safe; these are the best ED pills as these are capable of providing complete natural treatment by supplementing wide range of herbs which address all the possible causes of the problem.
3. Testosterone replacement. Before oral medications like Viagra, testosterone was routinely used to treat erectile dysfunction as it is central in the male sexual response, including the desire for sex and the process of getting an erection. Testosterone can be administered in a number of ways, for example orally, by means of an injection, skin patch, or subcutaneous (under the skin) pellet. 

^Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-controlled, double-blind, crossover study. - Author: The Male Clinic, Beverly Hills, CA, USA and David Geffen School of Medicine at University of California, Los Angeles, CA, USA. (14 June 2007)

Males gain erection due to hydraulic effect of blood, when brain senses arousal it rushes blood towards male genital organ where blood is absorbed by tissues which grow stiff and bigger to cause erection. Males having hindrances in this process due to poor sensation, blocked blood vessels, weak nerves, weak tissues or lethargic reproductive system are unable to gain erection. Tufan are reckoned as the best ED pills as these remove all sorts of hindrances to provide natural erectile dysfunction treatment, and as these are herbal ED pills hence do not cast any side effects.
The Science: Some studies have implied that feeding maca to domestic cattle increases sperm production, but there is very little data about any sexual effect on humans. One very small randomized double-bind trial of men with erectile dysfunction found that men taking maca extract reported a small increase in their ability to get erections. But so did the control group. As with the fenugreek study, a similar study with a larger group of people is needed to see whether any differences between the controls and the maca-eaters are real.
This calls for serious conservation strategies of plant targets in drug development borrowing from the indigenous knowledge of the local people. For instance, medicinal plants documented in this study like Warburgia ugandensis and Cirtopsis articulata used in erectile dysfunction and sexual impotence and ED need to be conserved based on their demand and medicinal value to the people. In the event of increased biotechnology and the use of modified living organisms in agriculture, health and environment, most people will go for natural products18,26. Furthermore, research in natural products is on the increase in both developed and developing nations to show that there is renewed interest in medicines of natural origin.
Dr. Niket Sonpal is the Associate Program Director of the Internal Medicine Residency at Brookdale Hospital Medical Center in Brooklyn and an Associate Professor at Touro College of Osteopathic Medicine. He’s a practicing Gastroenterologist and Hepatologist with a focus on Men’s and Women’s Health, and a regular contributor to Women’s health, Shape and Prevention Magazine.
The causes of ED are varies from one individual to another. For whatever cause, since an erection requires a precise sequence of events, ED can occur when any of the events is disrupted. This sequence includes nerve impulses in the brain, spinal column, and area around the penis, and response in muscles, fibrous tissues, veins, and arteries in and near the corpora cavernosa23. Thus, ED causes reported include, damage to nerves, arteries, smooth muscles, and fibrous tissues. These are often as a result of diseases, such as diabetes, kidney disease, chronic alcoholism, multiple sclerosis, atherosclerosis, vascular disease, and neurologic diseases that account for about 70 percent of ED cases23. NIH23 reported that between 35 and 50 percent of men with diabetes experience ED. NIH23 further reported that the usage of many common medicines such as blood pressure drugs, antihistamines, antidepressants, tranquilizers, appetite suppressants, and cimetidine (an ulcer drug) can produce ED as a side effect. Nevertheless, psychological factors such as stress, anxiety, guilt, depression, low self-esteem, and fear of sexual failure cause 10 to 20 percent of ED cases. In addition, men with a physical cause for ED frequently experience the same sort of psychological reactions (stress, anxiety, guilt, depression)23. Other possible causes are smoking, which affects blood flow in veins and arteries, and hormonal abnormalities, such as not enough testosterone23.

^Effects of Korean ginseng berry extract on sexual function in men with erectile dysfunction: a multicenter, placebo-controlled, double-blind clinical study. - Author: Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, and R&D Center, Amorepacific Corporation, Gyeonggi-do, South Korea (20 Dec 2012)
However, other studies have highlighted that men who weren’t on antidepressants showed no signs of improvement. With that said, this herb may be great to try if you’re experiencing ED and also on antidepressants. If not, try some of the other herbs on this list first and see if you like them more. You may get better results elsewhere! Also, this herb is not recommended for men who are on blood thinning medication, as this herb has been known to make people bleed more.
Many products contain undocumented “fillers” that can cause allergic reactions.  In recent years, the FDA has found over 300 herbal products that contain hidden, deceptively labeled, or dangerous ingredients4. And since 2015, the FDA has released public warnings on more than 160 ED supplements and “male enhancement” products found to contain dangerous ingredients and contaminants5 .   An independent study of FDA data, conducted in 2018, found almost 800 herbal supplements that contained unlisted ingredients6.

However, in some people there may be a genetic defect which prevents production of carnitine in body. Additionally, certain disorders of liver, kidneys and brain may also impair the production of enough carnitine. Some medications may also cause carnitine deficiency. In such cases, it becomes necessary to supplement carnitine to ensure normal smooth functioning of our body.
The researchers observed that there was increase in both scores (IIEF-5 and SAT-P) in both treatment groups after 12 weeks of treatment. However, this increase was much higher in Group 1 which was given 2400 mg/day maca extract supplementation compared to the placebo group. This clearly shows that the supplementation worked well in managing erectile dysfunction among these men.
In the East, many herbal tonics and preparations are used to assist the aging male improve his sexual drive or ability to perform penetrative sex by increasing sexual stimulation, erectile, ejaculatory, orgasmic and other responses for sexual function and satisfaction. The herbs and tonics act as or as “pick-me-ups” and energizing tonics which help the tired and fatigued male and those with sexual asthenia. The myths and realities concerning Tongkat Ali, sea horse, cobra meat and blood, animal penises and testicles amongst many other herbs and portions for oral intake or local application used by traditional “medical” practitioners and village doctors will be discussed.
E longifolia is a medicinal plant (family Simaroubaceae) native to Indonesia, Malaysia, Thailand, Vietnam and Laos. The root extract has been found to be the most powerful herbal aphrodisiac [17]. Tongkat ali extracts contain many alkaloids, quassinoids, phenolic compounds, tannins, high-molecular-weight glycoproteins and mucopolysaccharides. The main bioactive compounds are eurycomaoside, eurycolactone, eurycomalactone, eurycomanone and pasakbumin-B. It is considered to be natural ‘Viagra’. It increases sexual desire, and enhances performance and general well-being [17- 19]. In addition to its aphrodisiac effect, other medicinal effects, such as antimalarial, antibacterial, antipyretic, antiulcer and antitumour effects, have been reported [20,21]. Root decoction has been used as a general tonic (18,22]. Laboratory animal studies show that root extract enhances sexual characteristics and performance in rodents [22-25]. In a study involving a boar model, it was found that E longifolia root extract-treated boars increased sperm counts and semen volume; the effect was attributed to increased level of plasma testosterone [26]. Reports also suggest that E longifolia extract reverses the inhibitory effects of estrogen on testosterone production and spermatogenesis in rats [27]. Oral administration of E longifolia extract to inexperienced castrated male rats produced dose-dependent increases in sexual performance [28]. Zakaria et al [29] found that eurycomanone, a potential bioactive compound in the root extract of E longifolia, induced apoptosis in hepatocarcinoma (Hep G2) cells. Furthermore, their work suggested that eurycomanone was cytotoxic to Hep G2 cells and less toxic to normal Chang’s liver and WLR-68 cells. Tambi and Imran [19] investigated the effects of water-soluble extract of the root of E longifolia Jack and found that the extract increased semen volume, sperm concentration, percent of normal sperm morphology and sperm motility in male partners of subfertile couples with idiopathic infertility. Supplementation with E longifolia elevated the testosterone levels and upregulated osteoprotegerin gene expression in male Sprague-Dawley rats [30].
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In Uganda gender specific malfunctions or complications or diseases and conditions in reproductive health care are not given the due regard and the suffering persons tend to shy away. Sexual impotence and ED in men is considered a secret affair and the suffering persons keep quite or seek medical help in privacy. The psychologically affected men will try other women to test the viability of their manhood. The same is true, women with spouses with such erectile problems may be tempted to go outside their marriage vows to satisfy their sexual needs. This can also lead to HIV/AIDS exposure and result in broken homes and marriages12. The consequential outcomes of promiscuity, low self-esteem, polygamy, sexually transmitted diseases including HIV/AIDS are more detrimental to the individuals and society.

Tongkat Ali (Eurycoma longiflora) (Figure 7): this native plant found through SE Asia is used as an Aphrodisiac since 1996 (5). It has to be used regularly and works by enhancing the testosterone and cGMP production. Benefits are felt gradually over a period of time, mainly because it enhances the natural biological synthesis of testosterone. When the level is increased, health and vitality are restored. In studies on Mice, Tongkat Ali increases the number of times and duration of sexual performance of the animals under study (8) with testosterone levels increasing up to 440% in some animals. In a recent study on humans, 62% of subjects showed an increase of the free testosterone index indicating it’s biostimulatory effect on steroidogenesis. It has also been shown to increase sperm concentration and motility and increases energy in the individual by enhancing ATP production by 60% thru oxidative phosphorylation.


The search for a cure for erectile dysfunction (ED) dates back way before the introduction of Viagra in the 1990s. Natural aphrodisiacs, from ground rhinoceros horn topa chocolate, have long been used to increase libido, potency, or sexual pleasure. These natural remedies are also popular because they’re said to have fewer side effects than prescribed medications.
Those men that took 3gm of the root daily for 8 solid weeks are said to have improvement in their sexual intercourse frequently when compared to those that did not take it. As Maca is very safe generally, research shows that it increased the blood pressure in the user that have cardiovascular disease that took 0.6 gm of the root daily. Therefore, it is highly suggested that your daily intake must be less than 1 g/kg or 1g/2.2 pounds.

It doesn’t look good for the herbs. So far, there’s no data from controlled human trials that support the erection-promoting claims for any 5 of the most frequently used herbs. The icariin in the horny goat weed can help get it up, but since you’re getting the herb rather than a purified molecule, the concentration probably isn’t high enough to have much of an effect. Worse, it turns out that Viagra is much better at blocking that erection-killing enzyme than icariin is.
"Dan (28 years old) contacted me for online counseling and help with his sexual problems. Although he was in a steady relationship, Dan was afraid that he would lose his girlfriend due to his inability to maintain an erection. Even when he was aroused, Dan's erection was not as strong as he would have liked it to be and it did not last very long. When making love with his girlfriend, Dan would either ejaculate too quickly or his erection would disappear, leaving him embarrassed and his girlfriend unsatisfied. This had led to frustration and the couple were having arguments about lots of things. Dan had felt too ashamed to consult anyone face to face and chose the anonymous nature of online counseling to seek help for his problem. We worked together to draw up a healthy eating plan and a daily exercise routine and I started Dan on a course of Ikawe, three times daily. After about a week, there was a noticeable difference and Dan was beginning to feel aroused more often. A month later, Dan emailed me to say that he was a different man and that he and his girlfriend were making love every night! He felt proud that he was able to make love for longer and could satisfy his girlfriend as well as himself." - Michele Carelse, Clinical Psychologist
Garlic is one of the most common vegetables found at home that's beneficial in the treatment of sexual impotence. Dr. Mani says, "Garlic has often referred to as "the poor man's penicillin" because it serves as an effective antiseptic and immune booster. Being a sex rejuvenator, it can improve sexual activities that have been damaged due to an accident or a disease. Garlic is important for people who overindulge in sex to protect themselves from nervous exhaustion."
Move a muscle, but we're not talking about your biceps. A strong pelvic floor enhances rigidity during erections and helps keep blood from leaving the penis by pressing on a key vein. In a British trial, three months of twice-daily sets of Kegel exercises (which strengthen these muscles), combined with biofeedback and advice on lifestyle changes — quitting smoking, losing weight, limiting alcohol — worked far better than just advice on lifestyle changes.
Generally, erectile dysfunction (ED) is a neurovascular condition directly involving the endothelium of the corpora cavernosal arterial blood vessels in the penis, and is indirectly linked to cardiovascular diseases. The underlying mechanisms of ED are, however, complex and involve psychogenic, neurogenic, hormonal and vascular factors. ED occurs in aging men, with a prevalence of 52% in men 40 to 70 years of age [1-3]. Conditions that may cause ED include hypertension, diabetes, diseases of the prostate and heart, and obesity. ED may also be caused by the effects of certain medications as well as physical injury or anatomical deformity of the penis [4], or may result from endocrine disorders such as low testosterone, hypogonadism, adrenal insufficiency and hypothyroidism. Changes in blood flow to the male reproductive organs as a result of hardening of the arteries or atherosclerosis, hypertension and hypercholesterolemia may result in ED. It is generally accepted that there are vascular and neuropathic components to the pathophysiology of the disease, and ED has been recognized as a potential indicator of underlying cardiovascular disease. Chronic infections and/or inflammation of the prostate and irritation of the bladder may contribute to the pathogenesis of ED.

Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for intercourse. Because ED can have a strong psychological component, counseling with a psychotherapist or sex therapist often works. However, more often ED is a symptom of cardiovascular disease and diabetes, both of which can impair blood supply to the penis. In addition, many medications interfere with sexual functioning.
Tufan capsules are reckoned as the best ED pills as these possess only natural herbs as ingredients. Using Tufan herbal ED pills is safe as the herbs present in these pills are highly effective and completely safe; these are the best ED pills as these are capable of providing complete natural treatment by supplementing wide range of herbs which address all the possible causes of the problem.
From the bark of an evergreen tree in West Africa, Yohimbine has been used as a treatment for erectile dysfunction for the last 70 years. Like many over-the-counter and prescription erectile dysfunction medications, Yohimbine helps to increase the potentially stalled blood flow in the penis, increases overall sexual desire, and helps boost adrenaline. Yohimbine has also been known to help men gain, prolong, and maintain erections.
In fact, this herb has undergone many studies which link it very closely to Viagra. This is because this herb increases your overall sexual performance and desire and helps increase sperm count. There is actually a drink, whichmany people refer to as an aphrodisiac, called “Mulondo Wine,” which uses Mondia whitei as the main active ingredient. It’s termed an “aphrodisiac” because of its potential to increase sexual performance through an increased libidoand increased potency.
This is the vegetable root from Peru that meets the entire health benefits. If you can add this to your diet, you will surely see the difference. Maca is highly rich in iodine, amino acids, iron and magnesium. There are three types of Maca; black, red and yellow. The black one appears to get rid of stress as you boost your memory. Stress could cause ED.

It should be noted that Panax ginseng doeshave one major side effect: insomnia. However, compared to the side effects of other erectile dysfunction medications have, such as Viagra, many may consider this side effect to be worth it. Also, ginseng may react negatively if you’re taking any other medications, and with caffeine, so you should always talk to your doctor about your options before taking this step.
Ginseng is another adaptogen that increases the body’s ability to cope with physical, emotional, and environmental stress. The greater the body’s need for an adaptogen, the increasingly more active the substance becomes. All the adaptogens have been well studied and their safety repeatedly documented. Panax ginseng has been shown to improve overall sexual functioning in men with erectile dysfunction. Creams containing the compound are also available to treat premature ejaculation.

One study published in 2013 found that it releases nitric oxide, a feature that may contribute to an erectile response independent of testosterone level. Tribulus also increases testosterone and luteinizing hormone as well as DHEA. Tribulus is a favorite of athletes and body builders, some of whom have reported increased breast tissue at high dosages, due to the conversion of testosterone to estrogen. Although Tribulus has been used for centuries in the East, researchers in the West have yet to document its safety.
Acupuncture. Acupuncture has been used for centuries to treat ED and impotence in China. A recent review of studies on acupuncture for erectile dysfunction was published in the British Journal of Urology International. After reviewing four studies, the authors concluded that there was not sufficient evidence to say that acupuncture worked. However, some experts believe it's worth trying. "Acupuncture can work," says Gilbert. "It probably works best to treat the psychological component of ED. There is very little downside to trying it."
The study was conducted between April 2000 and March 2003 in western Uganda. To collect this data indirect asking of questions and investigations that do not refer or offend anyone were used since nobody especially men can say openly that they have this problem. These methods are explained in the textbook of ethnobotany and others have been used in the field for this kind of studies in Uganda and elsewhere in the world10,12,13,14,21. These methods included visiting the traditional healers to document the indigenous knowledge (IK), regarding medicinal plants used, gender and socio-cultural aspects and where the plants are harvested. Informal and formal conversations, discussions and interviews, market surveys and field visits were conducted.

Yohimbe A number of clinical trials have shown that the primary component of this bark from an African tree can improve sexual dysfunction associated with selective-serotonin reuptake inhibitors (SSRIs) used to treat depression. This herb has been linked to a number of side effects, including increased blood pressure, fast or irregular heartbeat, and anxiety. Yohimbe shouldn't be used without a doctor's supervision.
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