Extracts from medicinal plants have been used for considerable period of time in many parts of the world, particularly in Southwest Asia, to treat ED [16]. The current review focuses on four botanical medicinal plants, the roots of which are used in enhancing sexual performance and in the treatment of ED: Eurycoma longifolia Jack (tongkat ali); Chlorophytum borivilianum (safed musli); Withania somnifera (ashwagandha); and Pausinystalia johimbe (yohimbine, formerly known as Corynanthe johimbe).

This is the vegetable root from Peru that meets the entire health benefits. If you can add this to your diet, you will surely see the difference. Maca is highly rich in iodine, amino acids, iron and magnesium. There are three types of Maca; black, red and yellow. The black one appears to get rid of stress as you boost your memory. Stress could cause ED.
W somnifera (ashwagandha), also referred to as winter cherry (family Solanaceae), grows in Africa, the Mediterranean, India, Pakistan, Bangladesh, Afghanistan, South Africa, Egypt, Morocco, Congo and Jordan [36]. The roots of the plant contain steroid alkaloids and steroidal lactone, which are the main constituents of ashwagandha; these compounds are referred to as withanolides. Among the various alkaloids, withnine is the main constituent. The other alkaloids are somniferin, somnine, somniferine, withananine, pseudowithanine, tropine, pseudotropine, cuscohygrine, anferine and anhydrine. Two acyl steryl glucosides (sitoindoside VII and sitoindoside VIII) have been isolated from the root. The withanolides contain a C28 steroidal nucleus with a C9 side chain and six-membered lactone rings. Ashwagandha root also contains flavonoids and many ingredients of the withanolide class. It has several medicinal applications (aphrodisiac, liver tonic, anti-inflammatory agent, astringent), and is used to treat bronchitis, asthma, ulcers, insomnia, senility and dementia. Clinical trials and studies involving animal models support the use of ashwagandha for anxiety, cognitive and neurological disorders, inflammation and Parkinson’s disease. It also provides cryoprotective benefits to patients undergoing radiation and chemotherapy, and shows beneficial effects for nervous exhaustion. W somnifera is used as an aphrodisiac, sedative and rejuvenative, and is also used to treat chronic fatigue, dehydration, bone weakness, muscle weakness, loose teeth, impotency, premature ejaculation, debility, constipation, senility, rheumatism, nervous exhaustion, memory loss, drug withdrawal symptoms, anxiety and arthritis pain in the knee. Extracts from W somnifera inhibit transcription factor nuclear factor kappa B (NF-κB); thus, it acts as an anti-inflammatory agent. This has been attributed to its ability to interact with IKKB, a kinase that is responsible for the nuclear translocation of NF-κB and activation of inflammatory signalling pathways [37].

Ginseng, specifically “red ginseng,” is known as the “herbal Viagra” that helps puts to rest men’s bedroom woes. Red ginseng is when the root has been steamed and then dried. The ginseng root is the part of the plant that is mostly used as a natural remedy when in its supplement form. However, the plant must be grown for a minimum of five years before it can be used. In a 2008 review, seven studies on red ginseng and ED, ranging in dosages from 600 to 1,000 milligrams three times a day, were found to provide evidence for the effectiveness of the herb in ED treatment.


This African tree has proven to be effective and considered as one of the best herbal remedies for erectile dysfunction naturally. As a matter of fact, many clinical trials usually express improvement for almost all who is facing sexual challenges as a result of depression medications. However, this is not without some noticeable side effects like anxiety, irregular heartbeat and high blood pressure.
Currently, there are four orally active drugs are available to treat ED. These include: sildenafil citrate (Viagra [Pfizer, USA]), vardenafil hydrochloride (Levitra [Bayer, Germany]), tadalafil (Cialis [Eli Lilly, USA]) and avanafil (Stendra, Spedra [Vivus Inc, USA]). These drugs inhibit the enzyme phosphodiesterase type 5 (PDE-5), which is responsible for the hydrolysis of cGMP. PDE-5 inhibitors and cGMP act as effectors of dilation of smooth muscle of cavernosal bodies. PDE-5 inhibitors are contraindicated in patients taking any kind of nitrate therapy for angina, and may not be appropriate for men with certain health conditions, such as severe heart disease, heart failure, history of stroke or heart attack, uncontrolled high blood pressure or diabetes, and patients with pigmental retinopathy. PDE-5 inhibitors are less effective in men with diabetes and men who have been treated for prostate cancer. PDE-5 inhibitors are also not effective in men with retinitis pigmentosa, a genetic disease involving PDE-5 deficiency. The common side effects of PDE-5 inhibitors include gastrointestinal upset, headache, nasal congestion, back pain and dizziness. The PDE-5 inhibitors may interact with other medications including antihypertension drugs. Nonetheless, the PDE-5 inhibitors are generally safe and effective for most men. The primary mechanism of action of these drugs is through the mediation of NO. NO is one of the key molecules involved in ED. It is a short-lived, highly permeable, pleiotropic, gaseous molecule, secreted from the postganglionic cavernosal parasympathetic nerves, endothelium of the cavernosal blood vessels, platelets in the cavernosal sinuses and phagocytic cells (monocytes, macrophages and neutrophils). NO acts on platelets to inhibit platelets adhesion and aggregation. NO causes relaxation of the smooth muscle of the cavernosal blood vessels of the penis, leading to vasodilation, tumescence and stimulation. Release of NO in the corpus cavernosum of the penis during stimulation activates the enzyme guanylate cyclase, which results in increased levels of cGMP, producing smooth muscle relaxation in the corpus cavernosum and resulting in increased blood flow (5). NO is mainly produced from cavernosal nerves, which are nonadrenergic, noncholinergic nerves within the penis, and acting via its second messenger cGMP. It has been suggested that maintaining normal body weight and mild exercise, as well as dietary supplementation of folic acid, zinc, calcium, vitamin C, vitamin E and L-arginine, a precursor of NO, can support the biochemical pathway leading to NO release [6]. NO is an effector molecule that is involved in a number of intracellular functions such as vasorelaxation, endothelial regeneration, inhibition of leukocyte chemotaxis and platelet adhesion [7]. A small proportion of autonomic nerves do not release either Ach or norepinephrine [8]. For example, the cavernous nerves predominantly release NO in the penis. The exact mechanism is not known, but it is believed to be through increased intracellular calcium. Another gaseous molecule produced in the corpora cavernosa is hydrogen sulphide (H2S), which is also known to be involved in erectile function [9]. H2S activates ATP-sensitive potassium channels in smooth muscle cells. Some reports indicate that NO acts in large vessels and H2S in small vessels. A high level of tumour necrosis factor-alpha has been shown in ED patients [10]. Although current ED therapies using PDE-5 inhibitors are safe and effective, approximately 40% of ED patients do not respond to currently available treatment [11,12]. For these patients, herbal therapy may be useful.
DHEA. Testosterone is essential for a healthy libido and normal sexual function, and erectile dysfunction sufferers known to have low testosterone improve when placed on prescription testosterone replacement therapy. Similarly, studies have shown that taking over-the-counter supplements containing DHEA, a hormone that the body converts to testosterone and estrogen, can help alleviate some cases of ED. But DHEA can cause problems, including suppression of pituitary function, acne, hair loss and its long-term safety is unknown, says McCullough. For this reason, many experts discourage use of the supplements.
Some natural viagra supplements have been shown to increase nitric oxide levels and increase blood flow to the penis. But there are no true natural alternatives to prescription ED medication, like Viagra. But healthy food and (some) vitamins and supplements can improve your overall health and blood flow. And anything that improves blood flow can treat some of the causes of erectile dysfunction (as well as making you healthier).
Ginkgo biloba may increase blood flow to the penis. Researchers discovered the effect of gingko on ED when male participants in a memory enhancement study reported improved erections. Another trial saw improvement in sexual function in 76 percent of the men who were on antidepressant medication. This is why researchers believe that ginkgo may be effective for men who are experiencing ED due to medication.
Testosterone powers male primary and secondary sex characteristics, and maintains cardiovascular health in men. In addition to treating erectile dysfunction, testosterone replaces fat with lean muscle mass, increases energy level and sexual desire, and creates positive mood. Tongkat Ali is a favorite of body builders looking for increased lean body mass and strength.
Sleeping well is crucial for treating erectile dysfunction. As you may know, when we sleep, our body repairs itself. The brain gets the chance to remove waste and toxins. At the same time, your body produces testosterone, one essential substance for the sexual system to work properly. With the low level of testosterone, getting erections becomes difficult and this will lead to erectile dysfunction. Therefore, you need to have a 7-hour sleep every night to ensure the sexual health.
ED can also occur as a side effect of some medications, for example some high blood pressure medications such as certain diuretics and beta blockers. If you think that a medication you are taking has a negative effect on your sex life, you should discuss this with your prescribing doctor. Your doctor may be able to recommend an alternative treatment.
Know that you’re not alone.  20 million American men have ED. A study showed that one quarter of men under 40 also experience it. Though this is worrisome, it also means that these issues shouldn’t be solely discussed on the shady forums and message boards in which sketchy elixirs are advertised. If you think you may have ED, just know that you don’t have to go down a internet rabbit-hole to find answers.
"Dan (28 years old) contacted me for online counseling and help with his sexual problems. Although he was in a steady relationship, Dan was afraid that he would lose his girlfriend due to his inability to maintain an erection. Even when he was aroused, Dan's erection was not as strong as he would have liked it to be and it did not last very long. When making love with his girlfriend, Dan would either ejaculate too quickly or his erection would disappear, leaving him embarrassed and his girlfriend unsatisfied. This had led to frustration and the couple were having arguments about lots of things. Dan had felt too ashamed to consult anyone face to face and chose the anonymous nature of online counseling to seek help for his problem. We worked together to draw up a healthy eating plan and a daily exercise routine and I started Dan on a course of Ikawe, three times daily. After about a week, there was a noticeable difference and Dan was beginning to feel aroused more often. A month later, Dan emailed me to say that he was a different man and that he and his girlfriend were making love every night! He felt proud that he was able to make love for longer and could satisfy his girlfriend as well as himself." - Michele Carelse, Clinical Psychologist
L-arginine, or arginine, is an amino acid found in red meat, poultry, fish, and dairy products that helps expand blood vessels and increase blood flow. “The body uses this semi-essential amino acid as the primary building block for nitric oxide,” explains Harry Fisch, M.D., clinical professor of urology and reproductive medicine at Weill Cornell Medical College/New York Presbyterian Hospital.

Muira puama (Ptychopetalum olacoides): although used in Asia, this potency wood is actually the best known Amazonian folk medicine which increases libido and penile hardness. It acts as a nerve stimulant to heighten receptiveness to sexual stimuli as well as physical sensation of sex (9). Rich in sterols e.g., sitosterol, campesterol and lupol it activates the body’s receptors for hormones like testosterone to heighten libido and enhance performance (5). Also present are volatile oils like champor which helps restore sex drive and inner depth of libido and mental ability to be aroused.
The Claim: If you squint and have an excellent imagination, mature ginseng roots vaguely resemble a human body. That ties into folk ideas for finding medicines–in this case, the idea that a plant that looks like a person must contain materials that help sick people. Ginseng was traditionally used as a tonic to treat erectile dysfunction and low sexual drive in men (as well as many other complaints).
The medical ethnobotanical indigenous knowledge were collected by visiting traditional healers and documenting the medicinal plants used and other socio-cultural aspects allied with sexual impotence and erectile dysfunction. The methods used to collect the relevant information regarding the medicinal plants used included informal and formal discussions, field visits and focused semi-structured interviews.
According to the Cleveland Clinic, “because erectile dysfunction is caused by a complex set of psychosocial, neurologic, and vascular factors, a specific cause in a patient may remain ambiguous.” The root causes are often related to a blockage or dysfunction of blood vessels. For example, ED can be due to conditions like atherosclerosis or diabetes, hormonal imbalances or problems related to mental health. It’s been found that common causes typically include one or more of the following factors: (2)
Doing physical activities regularly boosts blood supply and improves your heart. This helps blood flow to all corners of the body, including the blood flow leading to the firm erections. Exercising also steps up your libido by releasing endorphins that make you feel good. Additionally, exercise produces nitric oxide that keeps the arteries open. Therefore, the flow of blood to the penis becomes speedier. Start with brisk walking at least 20 minutes a day or another activity to make more nitric oxide contributing to the maintenance of the erection and your health in general.
It should be noted that Panax ginseng doeshave one major side effect: insomnia. However, compared to the side effects of other erectile dysfunction medications have, such as Viagra, many may consider this side effect to be worth it. Also, ginseng may react negatively if you’re taking any other medications, and with caffeine, so you should always talk to your doctor about your options before taking this step.

As per Massachusetts Male Aging Study, it is stated that 50% of male population is experiencing this erectile dysfunction at some point in their lifetime, especially at the age of 40 or above. However, men who are suffering from this problem unable to talk about it and suffer in silence, as it leads to low self-esteem, depression and guilty feeling.
If you have symptoms of ED, it’s important to check with your doctor before trying any treatments on your own. This is because ED can be a sign of other health problems. For instance, heart disease or high cholesterol could cause ED symptoms. With a diagnosis, your doctor could recommend a number of steps that would likely improve both your heart health and your ED. These steps include lowering your cholesterol, reducing your weight, or taking medications to unclog your blood vessels.
×